Yeast cells can sometimes reverse the protein misfiling and clumping associated with diseases such as Alzheimer's, Parkinson's Huntington's and other incurable human neurodegenerative diseases. The new research from the University of Arizona, contradicts the idea that once prion proteins have changed into the shape that aggregates, the change is irreversible. The finding suggests artificially inducing stress responses may one day help develop treatments for diseases associated with misfiled prion proteins.
IN THIS EPISODETricia Serio, Professor and Head of the UofA's Department of Molecular and Cellular Biology
Tim Swindle, Ph. D, Director and Department Head of the University of Arizona's Lunar and Planetary Laboratory