August 10, 2017 / Modified sep 1, 2017 10:09 a.m.

Episode 92: Watching Molecules Perform their Functions

Using new techniques to watch enzyme proteins perform their functions.

Arizona Science 92 Molecules A look into a eukaryote cell to see how proteins are made. (PHOTO: Nicolle Rager, National Science Foundation)


Being able to see an object helps us to understand complex design and function quickly. That holds also true even for the microscopic machinery that drives our body. Using biomolecular nuclear magnetic resonance spectroscopy, the high resolution cousin of the MRI technique used in medicine, Wolfgang Peti can visualize enzyme proteins to understand their shape and mobility and how the mobility enables the enzymes to perform their specialized physiological functions. This is important as enzyme dysfunction commonly leads to disease.

In this episode:

Wolfgang Peti, Ph.D., Profesor, Department of Chemistry and Biochemistry
Leslie P. Tolbert, PhD, Regents' Professor in Neuroscience at the UA

Arizona Science
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