"Dr Keun is a Lecturer in Biological Chemistry in the Department of Biomolecular Medicine, Imperial College. He joined Imperial College in 2001 after completing undergraduate and postgraduate degrees from Oxford Univesity in Chemistry and Biochemistry. His research program centers on the application of metabolic profiling (metabonomics/metabolomics) to toxicology and oncology. Dr. Keun is using metabonomics to generate biomarkers for better detection, to predict an individual’s response to treatment, and identity new avenues for therapy.
He is currently investigating the potential of metabolic profiling to improve disease management in prostate, ovarian, and gastrointestinal cancers. These clinical projects are supported by laboratory research aimed at characterizing the disease and drug-resistance phenotypes in experimental models. He is also exploring the metabolic effects of carcinogens, as part of the EU-funded CARCINOGENOMICS consortium.
Dr. Keun has a keen interest in analytical and informatic development in metabolic profiling and he is a member of the editorial board for the Journal of Chemometrics. He continues to work as an investigatorin the Consortium for Metabonomic Toxicology (incl. Pfizer, Bristol-Myers Squibb, Servier & Sanofi-Aventis), that has generated the largest metabonomic resource of toxicological data presently available in the world today. The main focus for the COMET group is on expanding the use of metabonomics in drug discovery & development". - UA Department of Nutritional Sciences & College of Agriculture and Life Sciences